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S2Spire 2 Guide
S2Spire 2 Guide

A patch-aware Slay the Spire 2 guide database for returning players who want tier lists, cards, relics, bosses, and build notes without forum digging.

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Relic database

Neow Relics

Opening-risk relic family and first-path check

Neow Relics is an opening-focused relic page for separating first-floor stability from ordinary mid-run relic power.

Primary keyword: slay the spire 2 neow relicsLow confidence
Tier stance

Opening value before mid-run value

Decision point

First route, first shop, first elite

Opening note

Neow relics should be ranked by what they do before the run has normal context. A relic that is excellent on floor one may be ordinary later, and a powerful late-game relic may be too slow if the first route is already dangerous. The page should judge opening stability before ceiling.

Slay the Spire 2 Neow relic tier footage
Neow relic footage should answer first-path stability, downside, and early route questions.
  • Score the relic by the first three fights before late-game ceiling.
  • Record whether the downside changes first-shop or first-elite choices.
  • Link high-risk starts into returning-player route guidance.

When to downgrade it

Downgrade a Neow relic when its upside appears too late for the chosen route or when the downside makes the first elite, first shop, or first boss preparation worse.

Page Status

Version
Early Access
Updated
Jun 11, 2026
Category
Relic - Opening Family
NeowOpeningRelic Tier List

Source Footage

1 linked videos

All

These videos are queued for transcript review, screenshot selection, source playback, and original guide writing. We use them as research material, then rewrite the advice in our own structure.

1Sources
1Stills
1Playable
1Screened
Relic sourcescreened

Best Neow Relics

The BEST Neow Relics in Slay the Spire 2.mp4

Credit: Nerdy Hickey on YouTube

  • Support the Neow Relics page with relic-family footage.
  • Separate first-floor stability from ordinary mid-run relic power.
Watch videoOpen target page

Community Notes

Share run proof, matchup pressure, patch corrections, or exact video timestamps. Strong notes cite a patch, character, ascension, boss, or reward screen so they can become future page updates.

Run resultProof
Version namedPatch
Boss contextFight
TimestampClip

No approved notes yet. Be the first to submit a run note for review.

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Related Pages

Slay the Spire 2 Relic Tier List

Relic rankings by energy, consistency, build fit, boss pressure, and character synergy.

Slay the Spire 2 Relic List

A relic-list hub for Slay the Spire 2 with energy relics, boss relics, sustain relics, and tier-list links.

Slay the Spire 2 Boss Relics

A boss relic guide for Slay the Spire 2 focused on energy, downside management, and character-specific tradeoffs.

Slay the Spire 2 Returning Players Guide

A practical first-run guide for players who know the original game and need to reset old assumptions for the sequel.

Ancient Boon

Ancient Boon tracks opening relic decisions where the first route matters as much as the relic ceiling.

FAQ

Are Neow relics ranked like normal relics?

No. They need an opening-risk layer because their value appears before the deck, map, and reward pool are fully known.