Slay the Spire 2 Tier List

How to use this tier list

Use this as a patch-aware map, not a draft autopilot. Slay the Spire 2 rewards context: a powerful relic can be wrong for the current route, a strong character can still need conservative Act 1 picks, and a flashy card can be dead weight if the deck has not solved block or draw. The ranking is meant to tell returning players what deserves attention first.

• S tier means the item or plan can reshape the run when support appears.
• A tier means broadly strong and useful across many ordinary runs.
• B tier means playable but more dependent on patch, character, or matchup context.

Why confidence matters

Early Access rankings move quickly because small balance changes can change the breakpoints that make a deck survive. A tier entry with medium confidence is not weak; it means the page needs more reviewed runs, patch notes, and matchup footage before it should sound final.

• Raise confidence when multiple videos and runs show the same decision pattern.
• Lower confidence when the evidence is mostly highlight footage or one patch old.
• Rewrite notes after major card, relic, enemy, or boss changes.

Quick answer

The safest way to read the overall tier list is as a priority map. Start with repeatable plans, then check the specific card, relic, character, boss, or build page before forcing a choice. Exact Early Access rankings are needs verification after each major patch, especially when a page depends on new relic families or boss patterns.

Common mistake

The common mistake is treating the overall tier list as one universal draft order. A B-tier card that solves the next elite can be better than an S-tier payoff that does nothing now. Use the overall list to know what deserves attention, then use database pages to decide what the current run actually needs.